So wondering is there a point to where the Artafact and jewles need to be ajusted to get the best out of higher Mastery
Are you talking about the actual artefacts or the lightstones or both? I tend to use lightstone sets that provde benefits that exist outside mastery (mermaids wish 3, fishing time reduction, hunting set with extra crit and other stats, etc), so the mastery cap increase hasn't really affected those even though they also provide a little mastery bonus. Aside from that, it seems that just boosting total mastery as much as possible is still useful.
I am a guru 53 in cooking use the fundamentals of cooking set of stone and 2 Mastery Artafacts Tet Manos Cooking out fit a pen Ladel so at some point will the Stones or Artafact need chaging as you get even More Mastery