Region: NA
Character: Picklenose
For the most part, people only use "Escape" when the game bugs out and you get stuck. Most notably, boarding a boat at the wharfs with the infamous "Please try again later". Yes, I'm aware there are other options, such as going to character select.
I don't know what the cooldown on Escape is, but it's pretty large. PA shouldn't be time-gating us from workarounds for their defects.